Don enlists Charlie's help when the bodies of five young Asian girls found washed up are suspected of being infected with the Avian influenza virus.

To prevent the potential spread of the Avian flu, Don puts a rush on the investigation, which takes a surprising turn when David and Colby discover a clue on one of the girls' bodies. Meanwhile, Amita considers a move to Harvard University, which causes Charlie to re-evaluate his feelings for her.