Senator Martin Tallman and a local psychiatrist have one thing in common -- they both are found murdered during Don's shift. Though both of the murders took place in very different circumstances, they might have more in common than everyone initially thinks. Following a hunch, Don pursues the case as if the two murders are related, and in doing so he stumbles across a secret that has been covered up by the government for several years.

Dr. Fleinhardt finds out that his rival has declined to go to the International Space Station due to other obligations, so that he will be taking his place. Charlie has difficulty accepting that his friend and colleague will be gone for months.