As Thanksgiving nears, J.D. is stricken with appendicitis and gains a new and horrifying perspective on what it means to be a patient, and to make matters worse, it's Turk who will be doing the surgery. Elsewhere, Elliot resents the fact that J.D.'s patients prefer his care to her cold hands when she has to cover his cases for him, and Dr. Cox makes sure that his former medical mentor gets proper care from the nasty Dr. Kelso.