Special Agent Dana Scully is partnered with Special Agent Fox Mulder to validate his work in a division called The X-Files. While he is a believer in the paranormal, due to memories in which his sister was abducted by aliens, she is a skeptic and a scientist who prefers to look for rational, logical explanations.

After a number of Oregon high school teens begin to die mysteriously, Agents Scully and Mulder are called to investigate the matter. Mulder believes those murders are linked to alien abduction.