After man experiences a seizure but has no idea he has had it arrives at the hospital, House eagerly takes on the case. The team believes he has a bacterial infection, but Henry suffers a heart attack before the treatment for his infection is able to work and now needs a heart transplant. He chooses to approach the husband of the deceased woman, and feigns interest, only because he wants the heart. House and the team have to race against time to find out what the woman died of before they can use her heart for Henry.